TDNet Discover

Background: Currently available antidepressant therapies for major depressive disorder (MDD) and treatment-resistant depression (TRD) have many limitations. A substantial portion of MDD and TRD patients are shown to be resistant to the available ant…

Background: Wound closure is a key component in total joint arthroplasty. Methods for wound closure are an important consideration to avoid wound-related adverse events for the patient. Sutures and staples have been the mainstay of wound closure in …

Background and Purpose: Surgical fasciotomy has long been recognized as the definitive treatment for acute compartment syndrome. Several different methods of surgical wound closure are currently being practiced. Each method has advantages and disadv…

As the digital age marches on into new frontiers of online life, communication, and commerce, cell phone usage has evolved into a necessary and constant part of modern life. As a constantly updating tool, few updates have been made to the research i…

Background: Huntington’s disease (HD) is an autosomal dominant-inherited neurodegenerative disorder that results in cerebral atrophy leading to characteristic mood, movement, and memory changes that typically present between ages 30 to 50. Memory ch…

Background: Atrial fibrillation is the most common cardiac arrhythmia. Exercise is usually viewed as a protective factor against heart disease, including dysrhythmias. Exercise is defined as intense if it meets these criteria: greater than or equal …

Background: Around 322 million people battle with depression worldwide. There are no current guidelines or a standard of care to help treat patients with treatment resistant depression. The recent FDA approval of esketamine aims to help these treatm…

Introduction/Background: The inaccurate assessment of neuromuscular blockade (NMB) status by anesthesia providers places patients at risk for postoperative residual neuromuscular blockade (RNMB), with an incidence of up to 60% in the absence or inad…

Background: Cardiovascular disease (CVD) patients are at increased risk for mortality due to the progression of the disease and complications associated. Exercise has been shown to help improve cardiorespiratory fitness and to decrease mortality ris…

Background: This evidence-based medicine literature review compares outcomes of morbidity and mortality between surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR). Although originally approved for patients who…

Background: Multiple sclerosis (MS) is the most common debilitating autoimmune disease worldwide resulting in progressive disability in thousands of patients annually. Current treatments such as disease-modifying therapies (DMTs) aim to slow disease…

Background: Pediatric obesity is a nationwide public health concern that contributes greatly to the morbidity and mortality of the US population. Not only does obesity predispose a patient to various chronic health conditions, but it also affects th…

Background: Globally, depression is the most prevalent mental disorder that is associated with significant health and economic impacts. Common depression treatments include Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Selective Serotonin…

This Doctor of Nursing Practice (DNP) project targeted a highly significant issue of low cervical cancer screening rates among women aged 21 to 65 in an outpatient primary care clinic in Maryland. The subject of this project, cervical cancer was one…

BACKGROUND: Acute Respiratory Infections (ARIs) result in a significant amount of morbidity and mortality in the United States and around the world. Research has shown that basic principles of hand washing reduce the transmission of respiratory infe…